Antibody key to treating variant CJD, scientists find
Scientists at the University of Liverpool have determined the atomic structure of the 'binding' between a brain protein and an antibody that could be key to treating patients with diseases such as...
View ArticleVariant form of amyloid beta hinders amyloidogenesis, development of...
Alzheimer's disease causes misfolding and aggregation of a protein fragment known as amyloid beta and its deposition as plaques in the brain. This process triggers a cascade of event that leads to...
View ArticleStudy finds gene bringing together animal and human research in alcoholism
An important genetic study conducted through Mayo Clinic has identified vital new information concerning alcoholism in subjects with European ancestry, according to a recent issue of Alcohol: Clinical...
View ArticleMarking anorexia with a brain protein
Eating disorders are frequently seen as psychological or societal diseases, but do they have an underlying biological cause? A new study shows that the levels of a brain protein differ between healthy...
View ArticleAlzheimer's disease drug treats traumatic brain injury
The destructive cellular pathways activated in Alzheimer's disease are also triggered following traumatic brain injury, say researchers from Georgetown University Medical Center (GUMC). They say this...
View ArticleResearchers identify critical gene for brain development, mental retardation...
In laying down the neural circuitry of the developing brain, billions of neurons must first migrate to their correct destinations and then form complex synaptic connections with their new neighbors.
View ArticleNew findings about brain proteins suggest possible way to fight Alzheimer's
The action of a small protein that is a major villain in Alzheimer's disease can be counterbalanced with another brain protein, researchers at UT Southwestern Medical Center have found in an animal study.
View ArticleFine-tuning treatments for depression
New research clarifies how neurotransmitters like norepinephrine, serotonin, and dopamine, are regulated - a finding that may help fine-tune therapies for depression.
View ArticleAmyloid beta protein gets bum rap
While too much amyloid beta protein in the brain is linked to the development of Alzheimer's disease, not enough of the protein in healthy brains can cause learning problems and forgetfulness, Saint...
View ArticleStudy sheds light on brain's fear processing center
Breathing carbon dioxide can trigger panic attacks, but the biological reason for this effect has not been understood. A new study by University of Iowa researchers shows that carbon dioxide increases...
View ArticleNew stroke therapy successful in rats
People with impaired mobility after a stroke soon may have a therapy that restores limb function long after the injury, if a supplemental protein works as well in humans as it does in paralyzed rats.
View ArticleGene identified for sudden unexpected death in epilepsy
A mutation in a brain protein gene may trigger irregular heart beat and sudden death in people with epilepsy, according to new research in the April 14 issue of The Journal of Neuroscience. People with...
View ArticleBrain's master switch verified
The protein that has long been suspected by scientists of being the master switch allowing brains to function has now been verified by an Iowa State University researcher.
View ArticleStudy shows that major Alzheimer's risk gene causes alterations in shapes of...
Researchers at Mount Sinai School of Medicine have used a newly discovered class of biomarkers to investigate the possibility that the shape of brain protein deposits is different in people with...
View ArticleScreen yields drugs that could help treat fatal brain disorder
(PhysOrg.com) -- Using novel screens to sort through libraries of drugs already approved for use in human patients, a team of Wisconsin researchers has identified several compounds that could be used...
View ArticleMisfolded neural proteins linked to autism disorders
An international team of scientists, led by researchers at the University of California, San Diego, has identified misfolding and other molecular anomalies in a key brain protein associated with autism...
View ArticleGene therapy may be powerful new treatment for major depression
In a report published in the Oct. 20 issue of Science Translational Medicine, researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center say animal and human data suggest gene therapy to...
View Article'Magic number' 695 opens up new areas for Alzheimer's research
Alzheimer's disease is widely believed to be caused by the gradual accumulation in the brain of amyloid-beta peptide which is toxic to nerve cells. Amyloid beta peptide is formed from a protein known...
View ArticleDevelopment of a safer vaccine for Alzheimer’s disease
A new vaccine protects against memory problems associated with Alzheimer's disease, but without potentially dangerous side effects, a new animal study reports. The research was presented at...
View ArticleTherapy for fearsome brain disease could target blood
(PhysOrg.com) -- The aggregated proteins strewn about a deranged brain are the hallmark of one of the most feared and common neurodegenerative disorders on the planet: Alzheimers disease. But while...
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